Heat the olive oil in a large saucepan over medium heat.
Add the onion and garlic and cook for about 5 minutes, stirring occasionally, until the onion is soft.
Add the red pepper flakes, tomato sauce, brown sugar, tomato paste, honey, apple cider vinegar, molasses, yellow mustard, Worcestershire sauce, and oregano.
Bring the mixture to a boil, reduce the heat to low and simmer for 20 minutes, stirring occasionally.
Season with salt and pepper to taste.
Use the sauce to top your favorite pizza, or refrigerate in an airtight container for up to a week.